Searchable abstracts of presentations at key conferences in endocrinology

ea0081p718 | Thyroid | ECE2022

Clinical presentation and significance of thyroid dysfunctions secondary to PD-1/PD-L1 blockade cancer immunotherapy

Di Dalmazi Giulia , Elena Sorbo Sofia , Dudiez Andrea , Ciappini Beatrice , Cipolloni Ilaria , Russo Gianluca , Luisi Dimitri , Napolitano Giorgio , Bucci Ines

Background: Thyroid dysfunctions are among the most common immune-related adverse events (irAEs) following the administration of immune checkpoint inhibitors (ICIs) for malignancies. The pathogenesis of thyroid irAEs remains unclear and the clinical course can be multifaceted.Aim: Aims of this study were a) to describe the incidence and the clinical course of thyroid irAEs b) to determine the association between thyroid irAEs and overall survival (OS).</...